Diarrhea is one of the top dominant causes of death worldwide. To prevent the illness, a high-efficiency energy water disinfection method is needed. Electroporation is a promising method to achieve this goal, in which an electrical field is applied to cells to damage its’ cell membranes and kill the cell by the great change in cell permeability. This technology has good potential in killing bacteria under high enough voltage as a result. Yet, providing high voltage is usually costly. Triboelectric nanogenerators are introduced to step up the high voltage with a relatively low cost. Through the contact-separation or relative sliding between two materials that have opposite triobolary, an asymmetric charge distributes in the media, which induces AC electricity flow between two electrodes to balance the local potential distribution. The voltage created by the coupling of contact electrification and electrostatic induction can be very large and be able to achieve water disinfection. In this project, we are going to present a water disinfector by electroporation driven by triboelectric charge strengthened by nanowires as the cheap energy source.